Antidepressants worsen rapid-cycling course in bipolar depression: A STEP-BD randomized clinical trial

BACKGROUND: The use of antidepressants in rapid-cycling bipolar disorder has been controversial. We report the first randomized clinical trial with modern antidepressants on this topic. METHODS: As part of the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study, we analyzed...

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Publicado en:J Affect Disord
Autores principales: El-Mallakh, Rif S., Vöhringer, Paul A., Ostacher, Michael M., Baldassano, Claudia F., Holtzman, Niki S., Whitham, Elizabeth A., Thommi, Sairah B., Goodwin, Frederick K., Ghaemi, S. Nassir
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519402/
https://ncbi.nlm.nih.gov/pubmed/26142612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2015.04.054
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