Novel Effects of Simvastatin on Uterine Fibroids: In vitro and Patient-Derived Xenograft Mouse Model Study

OBJECTIVE: Uterine leiomyomas represent a common gynecologic problem with no satisfactory long-term medical treatment. The purpose of this study is to examine the effects of simvastatin on uterine leiomyoma, both in vitro and in vivo. STUDY DESIGN: This is a laboratory-based experimental study. For...

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Gepubliceerd in:Am J Obstet Gynecol
Hoofdauteurs: BORAHAY, Mostafa A., VINCENT, Kathleen, MOTAMEDI, Massoud, SBRANA, Elena, KILIC, Gokhan S., AL-HENDY, Ayman, BOEHNING, Darren
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519389/
https://ncbi.nlm.nih.gov/pubmed/25840272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2015.03.055
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