Adopting a Patient-Centered Approach to Primary Outcome Analysis of Acute Stroke Trials by Use of a Utility-Weighted Modified Rankin Scale

BACKGROUND AND PURPOSE: Although the modified Rankin Scale (mRS) is the most commonly employed primary endpoint in acute stroke trials, its power is limited when analyzed in dichotomized fashion and its indication of effect size challenging to interpret when analyzed ordinally. Weighting the seven R...

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Veröffentlicht in:Stroke
Hauptverfasser: Chaisinanunkul, Napasri, Adeoye, Opeolu, Lewis, Roger J., Grotta, James C., Broderick, Joseph, Jovin, Tudor G., Nogueira, Raul G., Elm, Jordan, Graves, Todd, Berry, Scott, Lees, Kennedy R., Barreto, Andrew D., Saver, Jeffrey L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519373/
https://ncbi.nlm.nih.gov/pubmed/26138130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.008547
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