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Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat

INTRODUCTION: Animal studies have shown that stress could induce epigenetic and transcriptomic alterations essential in determining the balance between adaptive or maladaptive responses to stress. We tested the hypothesis that chronic stress in rats deregulates coding and non-coding gene expression...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bradesi, Sylvie, Karagiannides, Iordanes, Bakirtzi, Kyriaki, Joshi, Swapna Mahurkar, Koukos, Georgios, Iliopoulos, Dimitrios, Pothoulakis, Charalabos, Mayer, Emeran A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519289/
https://ncbi.nlm.nih.gov/pubmed/26222740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130938
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