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Anthrax vaccine recipients lack antibody against the loop neutralizing determinant: a protective neutralizing epitope from Bacillus anthracis protective antigen

BACKGROUND: Epitope-focused immunogens can elicit antibody against the loop neutralizing determinant (LND), a neutralizing epitope found within the 2β2-2β3 loop of protective antigen (PA), which can protect rabbits from high-dose inhalation challenge with Bacillus anthracis Ames strain. Interestingl...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Oscherwitz, Jon, Quinn, Conrad P., Cease, Kemp B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519083/
https://ncbi.nlm.nih.gov/pubmed/25820066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.03.037
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