NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages

Blood monocytes are recruited to injured tissue sites and differentiate into macrophages, which protect against pathogens and repair damaged tissues. Reactive oxygen species (ROS) are known to be an important contributor to monocytes’ differentiation and macrophages’ function. NF-E2-related factor 2...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Song, Min-gu, Ryoo, In-geun, Choi, Hye-young, Choi, Bo-hyun, Kim, Sang-Tae, Heo, Tae-Hwe, Lee, Joo Young, Park, Pil-Hoon, Kwak, Mi-Kyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519053/
https://ncbi.nlm.nih.gov/pubmed/26222138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134235
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