Two Master Switch Regulators Trigger A40926 Biosynthesis in Nonomuraea sp. Strain ATCC 39727

The actinomycete Nonomuraea sp. strain ATCC 39727 produces the glycopeptide A40926, the precursor of dalbavancin. Biosynthesis of A40926 is encoded by the dbv gene cluster, which contains 37 protein-coding sequences that participate in antibiotic biosynthesis, regulation, immunity, and export. In ad...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Lo Grasso, Letizia, Maffioli, Sonia, Sosio, Margherita, Bibb, Mervyn, Puglia, Anna Maria, Alduina, Rosa
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518825/
https://ncbi.nlm.nih.gov/pubmed/25986904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00262-15
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