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DNA Electrochemistry shows DNMT1 Methyltransferase Hyperactivity in Colorectal Tumors
DNMT1, the most abundant human methyltransferase, is responsible for translating the correct methylation pattern during DNA replication, and aberrant methylation by DNMT1 has been linked to tumorigenesis. We have developed a sensitive signal-on electrochemical assay for the measurement of DNMT1 acti...
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| Publicado en: | Chem Biol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518711/ https://ncbi.nlm.nih.gov/pubmed/26120002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.05.019 |
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