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Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage.

We have used two selection techniques to study sequence-specific DNA recognition by the zinc finger, a small, modular DNA-binding minidomain. We have chosen zinc fingers because they bind as independent modules and so can be linked together in a peptide designed to bind a predetermined DNA site. In...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Choo, Y, Klug, A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972027/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.23.11163
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