Pharmacological approaches to the challenge of treatment-resistant depression

Although monoaminergic antidepressants revolutionized the treatment of Major Depressive Disorder (MDD) over a half-century ago, approximately one third of depressed patients experience treatment-resistant depression (TRD). Such patients account for a disproportionately large burden of disease, as ev...

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Bibliographic Details
Published in:Dialogues Clin Neurosci
Main Authors: Ionescu, Dawn F., Rosenbaum, Jerrold F., Alpert, Jonathan E.
Format: Artigo
Language:Inglês
Published: Les Laboratoires Servier 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518696/
https://ncbi.nlm.nih.gov/pubmed/26246787
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