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Evolutionary analysis of selective constraints identifies ameloblastin (AMBN) as a potential candidate for amelogenesis imperfecta

BACKGROUND: Ameloblastin (AMBN) is a phosphorylated, proline/glutamine-rich protein secreted during enamel formation. Previous studies have revealed that this enamel matrix protein was present early in vertebrate evolution and certainly plays important roles during enamel formation although its prec...

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Detalhes bibliográficos
Publicado no:BMC Evol Biol
Main Authors: Delsuc, Frédéric, Gasse, Barbara, Sire, Jean-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518657/
https://ncbi.nlm.nih.gov/pubmed/26223266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-015-0431-0
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