FGF21 protects against ox-LDL induced apoptosis through suppressing CHOP expression in THP1 macrophage derived foam cells

BACKGROUND: FGF21,as a member of the fibroblast growth factor superfamily, is an important endogenous regulator to systemic glucose and lipid metabolism. Elevated serum FGF21 levels have been reported in subjects with coronary heart disease and carotid artery plaques. The formation and apoptosis of...

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Vydáno v:BMC Cardiovasc Disord
Hlavní autoři: Li, En, Wang, Ting, Wang, Feng, Wang, Tao, Sun, Li-qiang, Li, Li, Niu, Shao-hui, Zhang, Jin-ying
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518604/
https://ncbi.nlm.nih.gov/pubmed/26223891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-015-0077-2
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