Genetic Variation in CYB5R3 is Associated with Methemoglobin Levels in Preterm Infants Receiving Nitric Oxide Therapy

BACKGROUND: In recent years, increasing numbers of preterm infants have been exposed to inhaled nitric oxide (iNO). This population has decreased methemoglobin (MetHb) reductase activity in their erythrocytes, which may increase the risk of MetHb toxicity. We sought to determine if genetic factors a...

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Publicat a:Pediatr Res
Autors principals: Fuller, Tyson D, Spracklen, Cassandra N, Ryckman, Kelli K, Knake, Lindsey A, Busch, Tamara D, Momany, Allison M, Murray, Jeffrey C, Dagle, John M
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518542/
https://ncbi.nlm.nih.gov/pubmed/25521918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.206
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