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Doxycycline Leads to Sterility and Enhanced Killing of Female Onchocerca volvulus Worms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial

Background. Ivermectin (IVM) has been the drug of choice for the treatment of onchocerciasis. However, there have been reports of persistent microfilaridermia in individuals from an endemic area in Ghana after many rounds of IVM, raising concerns of suboptimal response or even the emergence of drug...

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Bibliografski detalji
Izdano u:Clin Infect Dis
Glavni autori: Debrah, Alexander Yaw, Specht, Sabine, Klarmann-Schulz, Ute, Batsa, Linda, Mand, Sabine, Marfo-Debrekyei, Yeboah, Fimmers, Rolf, Dubben, Bettina, Kwarteng, Alexander, Osei-Atweneboana, Mike, Boakye, Daniel, Ricchiuto, Arcangelo, Büttner, Marcelle, Adjei, Ohene, Mackenzie, Charles D., Hoerauf, Achim
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518165/
https://ncbi.nlm.nih.gov/pubmed/25948064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ363
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