Doxycycline Leads to Sterility and Enhanced Killing of Female Onchocerca volvulus Worms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial

Background. Ivermectin (IVM) has been the drug of choice for the treatment of onchocerciasis. However, there have been reports of persistent microfilaridermia in individuals from an endemic area in Ghana after many rounds of IVM, raising concerns of suboptimal response or even the emergence of drug...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Debrah, Alexander Yaw, Specht, Sabine, Klarmann-Schulz, Ute, Batsa, Linda, Mand, Sabine, Marfo-Debrekyei, Yeboah, Fimmers, Rolf, Dubben, Bettina, Kwarteng, Alexander, Osei-Atweneboana, Mike, Boakye, Daniel, Ricchiuto, Arcangelo, Büttner, Marcelle, Adjei, Ohene, Mackenzie, Charles D., Hoerauf, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518165/
https://ncbi.nlm.nih.gov/pubmed/25948064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ363
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