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Crosstalk between monocytes and myometrial smooth muscle in culture generates synergistic pro-inflammatory cytokine production and enhances myocyte contraction, with effects opposed by progesterone

Both term and preterm parturition are characterized by an influx of macrophages and neutrophils into the myometrium and cervix, with co-incident increased peripheral blood monocyte activation. Infection and inflammation are strongly implicated in the pathology of preterm labour (PTL), with progester...

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Detalhes bibliográficos
Publicado no:Mol Hum Reprod
Main Authors: Rajagopal, S.P., Hutchinson, J.L., Dorward, D.A., Rossi, A.G., Norman, J.E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518137/
https://ncbi.nlm.nih.gov/pubmed/26002969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gav027
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