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Study of the Effects of ATP Suppliers and Thiol Reductants on Toxicity of Pioglitazone in Isolated Rat Liver Mitochondria

Pioglitazone (PG) is one of thiazolidinediones used for the treatment of type II diabetes mellitus. Some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. In the present study, the protective effect of some ATP suppliers are investigated against mitochon...

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Pubblicato in:Iran J Pharm Res
Autori principali: Rezaiean Mehrabadi, Abbas, Jamshidzadeh, Akram, Rashedinia, Marzieh, Niknahad, Hossein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shaheed Beheshti University of Medical Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518110/
https://ncbi.nlm.nih.gov/pubmed/26330870
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