Pharmacological mechanism underlying anti-inflammatory properties of two structurally divergent coumarins through the inhibition of pro-inflammatory enzymes and cytokines

BACKGROUND: The aim of the present study is to investigate the effects of two structurally divergent coumarins, calipteryxin (1) and (3’S,4’S)-3’,4’-disenecioyloxy-3’,4’-dihydroseselin (2) from Seseli recinosum, in lipopolysaccharide (LPS)-stimulated murine macrophages. METHODS: The nitrite producti...

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Bibliographic Details
Published in:J Inflamm (Lond)
Main Authors: Khan, Salman, Shehzad, Omer, Cheng, Mao-Sheng, Li, Rui-Juan, Kim, Yeong Shik
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517569/
https://ncbi.nlm.nih.gov/pubmed/26221081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0087-y
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