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Combined Trabectedin and anti-PD1 antibody produces a synergistic antitumor effect in a murine model of ovarian cancer

BACKGROUND: Monoclonal antibodies (mAb) that block programmed death (PD)-1 signaling pathway hold great potential as a novel cancer immunotherapy. Recent evidence suggests that combining with conventional, targeted or other immunotherapies, these mAb can induce synergistic antitumor responses. In th...

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Publicat a:J Transl Med
Autors principals: Guo, Zhiqiang, Wang, Haolin, Meng, Fandong, Li, Jie, Zhang, Shulan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517526/
https://ncbi.nlm.nih.gov/pubmed/26219551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0613-y
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