Blockade of bone morphogenetic protein signaling potentiates the pro-inflammatory phenotype induced by interleukin-17 and tumor necrosis factor-α combination in rheumatoid synoviocytes

INTRODUCTION: Bone morphogenetic proteins (BMPs) are multifunctional secreted growth factors regulating a broad spectrum of functions in numerous systems. An increased expression and production of specific BMPs have been described in the rheumatoid arthritis (RA) synovium. The aim of this study was...

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Udgivet i:Arthritis Res Ther
Main Authors: Varas, Alberto, Valencia, Jaris, Lavocat, Fabien, Martínez, Víctor G., Thiam, Ndiémé Ndongo, Hidalgo, Laura, Fernández-Sevilla, Lidia M., Sacedón, Rosa, Vicente, Angeles, Miossec, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517404/
https://ncbi.nlm.nih.gov/pubmed/26215036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0710-6
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