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Physiologically active hydrogel (in situ gel) of sparfloxacin and its evaluation for ocular retention using gamma scintigraphy

OBJECTIVE: Due to the structure and physiological barrier of eye, only 1% of instilled dose is available for action on the corneal surface. In this work, we developed and evaluated chitosan (pH sensitive) and gellan gum (ion sensitive) in situ gel of sparfloxacin to improve precorneal residence time...

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Detalles Bibliográficos
Publicado en:J Pharm Bioallied Sci
Autores principales: Gupta, Himanshu, Malik, Aqil, Khar, R. K., Ali, Asgar, Bhatnagar, Aseem, Mittal, Gaurav
Formato: Artigo
Lenguaje:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517321/
https://ncbi.nlm.nih.gov/pubmed/26229353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-7406.160015
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