Physiologically active hydrogel (in situ gel) of sparfloxacin and its evaluation for ocular retention using gamma scintigraphy

OBJECTIVE: Due to the structure and physiological barrier of eye, only 1% of instilled dose is available for action on the corneal surface. In this work, we developed and evaluated chitosan (pH sensitive) and gellan gum (ion sensitive) in situ gel of sparfloxacin to improve precorneal residence time...

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Detaylı Bibliyografya
Yayımlandı:J Pharm Bioallied Sci
Asıl Yazarlar: Gupta, Himanshu, Malik, Aqil, Khar, R. K., Ali, Asgar, Bhatnagar, Aseem, Mittal, Gaurav
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Medknow Publications & Media Pvt Ltd 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517321/
https://ncbi.nlm.nih.gov/pubmed/26229353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-7406.160015
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