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Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks

Cone snails are predatory marine gastropods characterized by a sophisticated venom apparatus responsible for the biosynthesis and delivery of complex mixtures of cysteine-rich toxin peptides. These conotoxins fold into small highly structured frameworks, allowing them to potently and selectively int...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lavergne, Vincent, Harliwong, Ivon, Jones, Alun, Miller, David, Taft, Ryan J., Alewood, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517256/
https://ncbi.nlm.nih.gov/pubmed/26150494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501334112
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