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GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time

The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock but also a seasonal clock. This neural network of ∼10,000 circadian oscillators encodes season-dependent day-length changes through a largely unknown mechanism. We show that region-intrinsic changes in the SCN fine...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Myung, Jihwan, Hong, Sungho, DeWoskin, Daniel, De Schutter, Erik, Forger, Daniel B., Takumi, Toru
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517217/
https://ncbi.nlm.nih.gov/pubmed/26130804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421200112
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