Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication

Herpesviruses require a nuclear egress complex (NEC) for efficient transit of nucleocapsids from the nucleus to the cytoplasm. The NEC orchestrates multiple steps during herpesvirus nuclear egress, including disruption of nuclear lamina and particle budding through the inner nuclear membrane. In the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Leigh, Kendra E., Sharma, Mayuri, Mansueto, My Sam, Boeszoermenyi, Andras, Filman, David J., Hogle, James M., Wagner, Gerhard, Coen, Donald M., Arthanari, Haribabu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517201/
https://ncbi.nlm.nih.gov/pubmed/26150520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511140112
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