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Estimating genetic effect sizes under joint disease-endophenotype models in presence of gene-environment interactions
Effects of genetic variants on the risk of complex diseases estimated from association studies are typically small. Nonetheless, variants may have important effects in presence of specific levels of environmental exposures, and when a trait related to the disease (endophenotype) is either normal or...
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| Publicado no: | Front Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516976/ https://ncbi.nlm.nih.gov/pubmed/26284107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00248 |
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