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Cocaine promotes oxidative stress and microglial-macrophage activation in rat cerebellum

Different mechanisms have been suggested for cocaine neurotoxicity, including oxidative stress alterations. Nuclear factor kappa B (NF-κB), considered a sensor of oxidative stress and inflammation, is involved in drug toxicity and addiction. NF-κB is a key mediator for immune responses that induces...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: López-Pedrajas, Rosa, Ramírez-Lamelas, Dolores T., Muriach, Borja, Sánchez-Villarejo, María V., Almansa, Inmaculada, Vidal-Gil, Lorena, Romero, Francisco J., Barcia, Jorge M., Muriach, María
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516895/
https://ncbi.nlm.nih.gov/pubmed/26283916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00279
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