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The Human Cytomegalovirus Lytic Cycle Is Induced by 1,25-Dihydroxyvitamin D3 in Peripheral Blood Monocytes and in the THP-1 Monocytic Cell Line

Human cytomegalovirus (HCMV) resides in a latent form in hematopoietic progenitors and undifferentiated cells within the myeloid lineage. Maturation and differentiation along the myeloid lineage triggers lytic replication. Here, we used peripheral blood monocytes and the monocytic cell line THP-1 to...

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Bibliographic Details
Published in:Virology
Main Authors: Wu, Shu-En, Miller, William E.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516672/
https://ncbi.nlm.nih.gov/pubmed/25965798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.04.004
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