VEGFR2 Gene Polymorphisms and Response to Anti-VEGF Therapy in Age-Related Macular Degeneration

PURPOSE: A previously published study demonstrated a pharmacogenetic association between the minor alleles of two VEGFR2 SNPs and greater improvement in visual acuity (VA) to treatment with ranibizumab, an anti-VEGF drug, in patients with neovascular age-related macular degeneration (nAMD). We evalu...

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Bibliographische Detailangaben
Veröffentlicht in:Ophthalmology
Hauptverfasser: Hagstrom, Stephanie A, Ying, Gui-shuang, Maguire, Maureen G, Martin, Daniel F, Gibson, Jane, Lotery, Andrew, Chakravarthy, Usha
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516643/
https://ncbi.nlm.nih.gov/pubmed/26028346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ophtha.2015.04.024
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