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Iron incorporation into MnSOD A (bacterial Mn-dependent superoxide dismutase) leads to the formation of a peroxidase/catalase implicated in oxidative damage to bacteria

BACKGROUND: Mn/Fe-superoxide dismutase (SOD) is a family of enzymes essential for organisms to be able to cope with oxygen. These enzymes bound to their classical metals catalyze the dismutation of the free radical superoxide anion (O(2)(•−)) to H(2)O(2) and molecular oxygen. E. coli has the mangane...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Ganini, Douglas, Petrovich, Robert M., Edwards, Lori, Mason, Ronald P.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516619/
https://ncbi.nlm.nih.gov/pubmed/25964067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2015.05.006
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