High glucose attenuates VEGF expression in rat multipotent adult progenitor cells in association with inhibition of JAK2/STAT3 signalling

This study was to investigate the effect of high glucose (HG) on vascular endothelial growth factor (VEGF) expression in bone marrow stem cells and JAK2/STAT-3 signalling. Adult rat bone marrow multipotent progenitor cells (rMAPCs) were cultured to evaluate VEGF expression (both mRNA and protein) wi...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Liu, Zehao, Lei, Minxiang, Jiang, Yuehua, Hao, Hong, Chu, Ling, Xu, Jian, Luo, Min, Verfaillie, Catherine M, Zweier, Jay L, Liu, Zhenguo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2009
Fag:
Tissue Remodeling/Regeneration
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516498/
https://ncbi.nlm.nih.gov/pubmed/18798867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00502.x
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