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Departure gate of acidic Ca(2+) confirmed

More potent, but less known than IP(3) that liberates Ca(2+) from the ER, NAADP releases Ca(2+) from acidic stores. The notion that TPC channels mediate this Ca(2+) release was questioned recently by studies suggesting that TPCs are rather PI(3,5)P(2)-activated Na(+) channels. Ruas et al (2015) now...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Jentsch, Thomas J, Hoegg-Beiler, Maja B, Vogt, Janis
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516426/
https://ncbi.nlm.nih.gov/pubmed/26022292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591884
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