Ethanol and Nicotine Interaction within the Posterior Ventral Tegmental Area in Male and Female Alcohol-Preferring Rats: Evidence of Synergy and Differential Gene Activation in the Nucleus Accumbens Shell

RATIONALE: Ethanol and nicotine are frequently co-abused. The biological basis for the high co-morbidity rate is not known. Alcohol-preferring (P) rats will self-administer EtOH or nicotine directly into the posterior ventral tegmental area (pVTA). OBJECTIVE: The current experiments examined whether...

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Publicat a:Psychopharmacology (Berl)
Autors principals: Truitt, William A., Hauser, Sheketha R., Deehan, Gerald A., Toalston, Jamie E., Wilden, Jessica A., Bell, Richard L., McBride, William J., Rodd, Zachary A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516277/
https://ncbi.nlm.nih.gov/pubmed/25155311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3702-3
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