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Development and characterization of nanoparticulate formulation of a water soluble prodrug of dexamethasone by HIP complexation

The objective of this study was to develop and characterize a nanoparticulate-based sustained release formulation of a water soluble dipeptide prodrug of dexamethasone, valine–valine-dexamethasone (VVD). Being hydrophilic in nature, it readily leaches out in the external aqueous medium and hence par...

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Detalhes bibliográficos
Publicado no:J Microencapsul
Main Authors: Gaudana, Ripal, Parenky, Ashwin, Vaishya, Ravi, Samanta, Swapan K., Mitra, Ashim K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516232/
https://ncbi.nlm.nih.gov/pubmed/20939702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02652048.2010.520093
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