Llwytho...

Transporter-Targeted Lipid Prodrugs of Cyclic Cidofovir: A Potential Approach for the Treatment of Cytomegalovirus Retinitis

Cidofovir (CDF) and its cyclic analogue (cCDF) have shown potential in vitro and in vivo antiviral activity against cytomegalovirus (CMV) retinitis. However, hydrophilic nature of CDF may affect cell permeation across lipophilic epithelium and thus limit its effectiveness in the treatment of CMV ret...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pharm Sci
Prif Awduron: Gokulgandhi, Mitan R., Barot, Megha, Bagui, Mahuya, Pal, Dhananjay, Mitra, Ashim K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516231/
https://ncbi.nlm.nih.gov/pubmed/22499243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23140
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