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Targeting brain cells with glutathione-modulated nanoliposomes: in vitro and in vivo study

BACKGROUND: The blood–brain barrier prevents many drug moieties from reaching the central nervous system. Therefore, glutathione-modulated nanoliposomes have been engineered to enhance the targeting of flucytosine to the brain. METHODS: Glutathione-modulated nanoliposomes were prepared by thin-film...

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Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autori principali: Salem, Heba F, Ahmed, Sayed M, Hassaballah, Ashraf E, Omar, Mahmoud M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516201/
https://ncbi.nlm.nih.gov/pubmed/26229435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S85302
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