Colon-targeted delivery of budesonide using dual pH- and time-dependent polymeric nanoparticles for colitis therapy

Single pH-dependent drug delivery systems have been widely used for colon-targeted delivery, but their efficiency is often hampered by the variation in gut pH. To overcome the limitation of single pH-dependent delivery systems, in this study, we developed and evaluated the therapeutic potential of b...

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Guardat en:
Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Naeem, Muhammad, Choi, Moonjeong, Cao, Jiafu, Lee, Yujeong, Ikram, Muhammad, Yoon, Sik, Lee, Jaewon, Moon, Hyung Ryong, Kim, Min-Soo, Jung, Yunjin, Yoo, Jin-Wook
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516197/
https://ncbi.nlm.nih.gov/pubmed/26229440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S88672
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