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Predicting treatment response in castration-resistant prostate cancer: could androgen receptor variant-7 hold the key?

There is an emerging interest in understanding mechanisms of response and resistance to next-generation hormonal therapies: abiraterone and enzalutamide. While many explanations for resistance to these agents have been postulated, the importance of androgen receptor splice variants is gaining moment...

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Detalles Bibliográficos
Publicado en:Expert Rev Anticancer Ther
Autor Principal: Antonarakis, Emmanuel S
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516117/
https://ncbi.nlm.nih.gov/pubmed/25547524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2015.999044
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