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The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

Among the identified thousands of circular RNAs (circRNA) in humans and animals, Cdr1as (also known as CiRS-7) was recently demonstrated to act as a powerful miR-7 sponge/inhibitor in developing midbrain of zebrafish, suggesting a novel mechanism for regulating microRNA functions. MiR-7 is abundantl...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Xu, Huanyu, Guo, Sen, Li, Wei, Yu, Ping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515639/
https://ncbi.nlm.nih.gov/pubmed/26211738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12453
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