Identification of the Scopularide Biosynthetic Gene Cluster in Scopulariopsis brevicaulis

Scopularide A is a promising potent anticancer lipopeptide isolated from a marine derived Scopulariopsis brevicaulis strain. The compound consists of a reduced carbon chain (3-hydroxy-methyldecanoyl) attached to five amino acids (glycine, l-valine, d-leucine, l-alanine, and l-phenylalanine). Using t...

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Publicat a:Mar Drugs
Autors principals: Lukassen, Mie Bech, Saei, Wagma, Sondergaard, Teis Esben, Tamminen, Anu, Kumar, Abhishek, Kempken, Frank, Wiebe, Marilyn G., Sørensen, Jens Laurids
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515620/
https://ncbi.nlm.nih.gov/pubmed/26184239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13074331
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