Differential transcriptomic and metabolic profiles of M. africanum- and M. tuberculosis-infected patients after, but not before drug treatment

The epidemiology of Mycobacterium tuberculosis (Mtb) and M. africanum (Maf) suggest differences in their virulence, but the host immune profile to better understand the pathogenesis of tuberculosis (TB) have not been studied. We compared the transcriptomic and metabolic profiles between Mtb and Maf-...

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Veröffentlicht in:Genes Immun
Hauptverfasser: Tientcheu, Leopold D., Maertzdorf, Jeroen, Weiner, January, Adetifa, Ifedayo M., Mollenkopf, Hans-Joachim, Sutherland, Jayne S., Donkor, Simon, Kampmann, Beate, Kaufmann, Stefan H. E., Dockrell, Hazel M., Ota, Martin O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515549/
https://ncbi.nlm.nih.gov/pubmed/26043170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.21
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