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Evidence for glycosylation as a regulator of the pigmentary system: key roles of sialyl(α2-6)gal/GalNAc-terminated glycans in melanin synthesis and transfer

The major regulators of melanogenesis are glycoproteins, however no role for glycosylation in the pathway has yet been described. We stained skin biopsies and melanocyte-keratinocyte co-cultures with a panel of 20 lectins as oligosaccharide markers. Notably, the Elderberry Bark Lectin (EBL/SNA) stai...

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Detalhes bibliográficos
Publicado no:Glycoconj J
Main Authors: Diwakar, Ganesh, Klump, Vincent, Lazova, Rossitza, Pawelek, John
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515250/
https://ncbi.nlm.nih.gov/pubmed/26194059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-015-9605-7
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