GTSE1 expression represses apoptotic signaling and confers cisplatin resistance in gastric cancer cells

BACKGROUND: Platinum based therapy is commonly used in the treatment of advanced gastric cancer. However, resistance to chemotherapy is a major challenge that causes marked variation in individual response rate and survival rate. In this study, we aimed to identify the expression of GTSE1 and its co...

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Udgivet i:BMC Cancer
Main Authors: Subhash, Vinod Vijay, Tan, Shi Hui, Tan, Woei Loon, Yeo, Mei Shi, Xie, Chen, Wong, Foong Ying, Kiat, Zee Ying, Lim, Robert, Yong, Wei Peng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514980/
https://ncbi.nlm.nih.gov/pubmed/26209226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1550-0
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