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Improved Methods to Generate Spheroid Cultures from Tumor Cells, Tumor Cells & Fibroblasts or Tumor-Fragments: Microenvironment, Microvesicles and MiRNA

Diagnostic and prognostic indicators are key components to achieve the goal of personalized cancer therapy. Two distinct approaches to this goal include predicting response by genetic analysis and direct testing of possible therapies using cultures derived from biopsy specimens. Optimally, the latte...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lao, Zheng, Kelly, Catherine J., Yang, Xiang-Yang, Jenkins, W. Timothy, Toorens, Erik, Ganguly, Tapan, Evans, Sydney M., Koch, Cameron J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514828/
https://ncbi.nlm.nih.gov/pubmed/26208323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133895
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