Simvastatin Increases Fibulin-2 Expression in Human Coronary Artery Smooth Muscle Cells via RhoA/Rho-Kinase Signaling Pathway Inhibition

The composition and structure of the extracellular matrix (ECM) in the vascular wall and in the atherosclerotic plaque are important factors that determine plaque stability. Statins can stabilize atherosclerotic plaques by modulating ECM protein expression. Fibulins are important components of the E...

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Bibliographic Details
Published in:PLoS One
Main Authors: Serra, Noemí, Rosales, Roser, Masana, Lluís, Vallvé, Joan-Carles
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514789/
https://ncbi.nlm.nih.gov/pubmed/26207907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133875
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