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ALS drug development: Reflections from the past and a way forward

Tremendous advances in our understanding of pathogenesis of amyotrophic lateral sclerosis (ALS) have provided a rich pipeline of drugs for clinical trialists. At least 32 unique compounds have been tested. Nevertheless, riluzole is currently the only treatment that prolongs survival. We present a cr...

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Publicat a:Neurotherapeutics
Autors principals: Aggarwal, Swati, Cudkowicz, Merit
Format: Artigo
Idioma:Inglês
Publicat: Springer New York 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514695/
https://ncbi.nlm.nih.gov/pubmed/19019302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2008.08.002
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