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Prolonged period of cortical plasticity upon redox dysregulation in fast-spiking interneurons

BACKGROUND: Oxidative stress and the specific impairment of peri-somatic GABA circuits are hallmarks of the schizophrenic brain and its animal models. Proper maturation of these fast-spiking inhibitory interneurons normally defines critical periods of experience-dependent cortical plasticity. METHOD...

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Publicat a:Biol Psychiatry
Autors principals: Morishita, Hirofumi, Cabungcal, Jan-Harry, Chen, Ying, Do, Kim Q., Hensch, Takao K.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514575/
https://ncbi.nlm.nih.gov/pubmed/25758057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.12.026
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