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Deficiency of Superoxide Dismutase Impairs Protein C Activation and Enhances Susceptibility to Experimental Thrombosis

OBJECTIVE: Clinical evidence suggests an association between oxidative stress and vascular disease, and in vitro studies have demonstrated that reactive oxygen species (ROS) can have prothrombotic effects on vascular and blood cells. It remains unclear, however, whether elevated levels of ROS accele...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Dayal, Sanjana, Gu, Sean X, Hutchins, Ryan D., Wilson, Katina M., Wang, Yi, Fu, Xiaoyun, Lentz, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514539/
https://ncbi.nlm.nih.gov/pubmed/26069236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305963
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