Oral administration of recombinant Neisseria meningitidis PorA genetically fused to H. pylori HpaA antigen increases antibody levels in mouse serum, suggesting that PorA behaves as a putative adjuvant

The Neisseria meningitidis outer membrane protein PorA from a Chilean strain was purified as a recombinant protein. PorA mixed with AbISCO induced bactericidal antibodies against N. meningitidis in mice. When PorA was fused to the Helicobacter pylori HpaA antigen gene, the specific response against...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Vasquez, Abel E, Manzo, Ricardo A, Soto, Daniel A, Barrientos, Magaly J, Maldonado, Aurora E, Mosqueira, Macarena, Avila, Anastasia, Touma, Jorge, Bruce, Elsa, Harris, Paul R, Venegas, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514328/
https://ncbi.nlm.nih.gov/pubmed/25750999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1011011
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