Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system

Administering vaccines directly to mucosal surfaces can induce both serum and mucosal immune responses. Mucosal responses may prevent establishment of initial infection at the port of entry and subsequent dissemination to other sites. The sublingual route is attractive for mucosal vaccination, but b...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: White, Jessica A, Blum, Jeremy S, Hosken, Nancy A, Marshak, Joshua O, Duncan, Lauren, Zhu, Changcheng, Norton, Elizabeth B, Clements, John D, Koelle, David M, Chen, Dexiang, Weldon, William C, Steven Oberste, M, Lal, Manjari
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
LICENSED VACCINES/Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514067/
https://ncbi.nlm.nih.gov/pubmed/25483682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.32253
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