Development of one-step real-time PCR assay for titrating trivalent live attenuated influenza vaccines

Traditionally, infectivity of a trivalent live attenuated influenza vaccines (LAIVs) is titrated by determining the 50% egg infectious dose assay (EID(50)) or plaque forming units (PFU), which requires specific monoclonal antibodies to neutralize 2 strains while estimating the titer of the non-neutr...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Zang, Yang, Du, Dongchuan, Ge, Peng, Xu, Yongqing, Liu, Xintao, Zhang, Yan, Su, Weiheng, Kiseleva, Irina, Rudenko, Larisa, Xu, Fei, Kong, Wei, Jiang, Chunlai
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
INFLUENZA/Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514063/
https://ncbi.nlm.nih.gov/pubmed/25483696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.34453
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