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α-Tocopherols modify the membrane dipole potential leading to modulation of ligand binding by P-glycoprotein

α-Tocopherol (vitamin E) has attracted considerable attention as a potential protective or palliative agent. In vitro, its free radical-scavenging antioxidant action has been widely demonstrated. In vivo, however, vitamin E treatment exhibits negligible benefits against oxidative stress. α-Tocophero...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Davis, Sterenn, Davis, Benjamin M., Richens, Joanna L., Vere, Kelly-Ann, Petrov, Peter G., Winlove, C. Peter, O’Shea, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513995/
https://ncbi.nlm.nih.gov/pubmed/26026069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M059519
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